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Semax research vial

SEMAX

Neuro Research Peptide
In Vitro Research Compound

A synthetic heptapeptide derived from ACTH (4–10) — studied in the context of neuroprotection, cognition, and nootropic research.

Size
$35
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Research Use Only. Product is intended solely for laboratory and research purposes. Not for human or animal consumption. By purchasing, you confirm this product will be used for in vitro research only.

Semax
Research Compound

Certificate of Analysis

Independently 8× tested by a US ISO/IEC 17025 lab.

8× Testing ISO 17025 Pass
99.38%
Purity
✓ Passed full QC panel
VariantSemax · 10 mg
Lot #2026-001
Labeled10 mg
Actual10.37 mg
TestedSep 1, 2026
Full QC PanelISO/IEC 17025
  • Purity (HPLC)99.38% ✓
  • Net Peptide Content10.37 mg ●
  • Identity (HPLC-RTM)Semax ✓
  • Heavy Metals (ICP-MS)Not Detected ✓
  • Sterility (PCR)No Growth ✓
  • Endotoxin (USP <85>)NMT 0.05 EU/mL ●
  • Fentanyl ScreenNot Detected ✓
✓ passed a specification● reported value, no threshold
View full COA
Issued by ILS Laboratories · COA-2026-NV5FWR

Batch-specific Certificates of Analysis (COAs) are available, documenting full testing results across all verification protocols for research traceability.

Description

Overview & research context

Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH 4–10). It has been studied in the scientific literature in the context of neuroprotection research, cognition and nootropic research, and neurotrophic (BDNF-pathway) research.

Neuroprotection
Neuroprotective research
Cognition
Cognitive & nootropic research
Neurotrophic
BDNF-pathway research
CAS Number80714-61-0
Molecular FormulaC₃₇H₅₁N₉O₁₀S
Molecular Weight813.92 g/mol
Code NameACTH (4–10) analog
SequenceMet-Glu-His-Phe-Pro-Gly-Pro
Storage Requirements

Stability Information

Avoid freeze/thaw cycles Protect from light Keep refrigerated
Lyophilized (powder)
−20°C
24+ months
Reconstituted
2–8°C
~30 days
  • Store lyophilized powder vials in the freezer when possible.
  • After reconstitution, refrigerate at 2–8°C and protect from light and heat.
  • Use within a typical research handling window after mixing. Swirl gently — never shake.
  • Use sterile technique during reconstitution.
For laboratory research use only
Research References

Peer-reviewed evidence

Peer-reviewed literature relevant to Semax. Each links to its source record.

  1. PubMed — preclinical literature on Semax NIH index of peer-reviewed papers — mechanisms, reviews, and preclinical / in-vitro findings
  2. PubChem — chemical identity of Semax NCBI compound record: structure, formula, identifiers, and physical properties
  3. Semax affects copper-induced Aβ aggregation and amyloid formation in artificial membrane models ACS Chemical Neuroscience · 2022 · Sciacca et al. · Amyloid-β / Cu²⁺ · DOI 10.1021/acschemneuro.1c00707
  4. Semax, a copper-chelator peptide, lowers Cu(II)-catalyzed ROS production and Aβ cytotoxicity Bioinorganic Chemistry & Applications · 2025 · Tomasello et al. · Metal-ion stripping / redox silencing · PMID 40496623
  5. Effect of Semax, an ACTH(4-10) analogue, on intracellular calcium dynamics in rat brain neurons Bulletin of Experimental Biology & Medicine · 2025 · Kolbaev et al. · PMID 41171324
Independent laboratory literature and compound data

Research context only. The papers above are independent published studies, many in laboratory animal models — not medical advice, and not a claim that any applies to this product. Sold strictly for in vitro laboratory research; not for human or animal use.

Terms & Compliance

Terms of sale

Eligibility

Buyer is 21 or older and a qualified research professional or institution conducting lawful scientific research.

Permitted use

In vitro laboratory research and education only — never for human or animal consumption, injection, administration, veterinary or any in vivo use.

Buyer responsibility

Lawful handling, storage, use and disposal of all materials, in accordance with applicable law.

Regulatory status

Not evaluated or approved by the FDA; not intended to diagnose, treat, cure, mitigate or prevent any disease.

Purchase constitutes acceptance of these terms. To the fullest extent permitted by law, Ivory Compounds and its affiliates disclaim liability arising from misuse, mishandling, or unauthorized use.